밀드 우드 리그닌과 크라프트 리그닌을 사용한 침전법과 투석법으로 리그닌 나노입자 합성에 관한 비교 연구

아즈마 파크할1*, 무하마드 아자즈 아흐메드2, 최준원1,2

(1서울대학교 국제농업기술대학원, 2서울대학교 그린바이오과학기술연구원)

A Comparative Study on the Synthesis and Characterization of Milled Wood Lignin and Kraft Lignin Nanoparticles

Azma Fakhar1*,  Muhammad Ajaz Ahmed2, Joon Weon Choi1,2

(1Graduate School of International Agricultural Technology, Seoul National University,

2Institutes of Green-Bio Science and Technology, Seoul National University)

Abstract: Lignin, a natural, abundant biopolymer, is primarily found in the cell walls of plants and has become a significant focus of research due to its sustainable and versatile nature. Lignin nanoparticles (LNPs) have attracted attention for their potential use in a diverse range of applications such as drug delivery, wound healing, environmental remediation, and as nanofillers for composites. The synthesis of LNPs from lignin can be achieved through various methods, including dialysis and nanoprecipitation. This study compares the synthesis and characterization of nanoparticles derived from two types of lignin: Kraft lignin (KL) and Milled wood lignin (MWL). Both types of lignin were used to prepare NPs at three different concentrations (1%, 5%, and 10%) using the dialysis method. The resulting nanoparticle sizes for KL were 500-700nm, and for MWL, 550nm-650nm, respectively. The zeta potentials for KL NPs ranged from -41 to -39 mV, while MWL NPs showed zeta potentials between -40 and -42 mV, indicating stable dispersions. In contrast, nanoprecipitation produced significantly smaller nanoparticles with sizes ranging from 110 to 150 nm at the same concentrations, with zeta potentials of -28 to -33 mV. The smaller particle size achieved through nanoprecipitation enhances the surface area, which is beneficial for applications such as antibacterial activity, UV protection, and nanofiller adsorbents. The results highlight the influence of the synthesis method on the size and stability of lignin nanoparticles, emphasizing their potential for use in biomedical, environmental, and industrial fields.

Keywords: Lignin nanoparticles, Nanoprecipitation, Dialysis, Zeta size, Zeta potential

사사: 본 연구는 ㅇㅇ사업(No. 2012000210002)의 지원에 의해 이루어진 것임.